Publications

Please contact Shyamalika Gopalan directly if you have any issues accessing our publications.

Peer-reviewed publications

* Indicates co-first authorship

2024

DV Zavala, N Dzikowski, S Gopalan, KD Harrington, G Pasquini, J Mogle, K Reid, M Sliwinski, JE Graham-Engeland, C Engeland, K Bernard, K Veeramah, SB Scott. Epigenetic age acceleration and chronological age: associations with cognitive performance in daily life. The Journals of Gerontology: Series A. 79(1):glad242. DOI: 10.1093/gerona/glad242

2023

G Meeks, BM Henn, S Gopalan. Genetic differentiation at probe SNPs leads to spurious results in meQTL discovery. Communications Biology. 6(1):1295. DOI: 10.1038/s42003-023-05658-5

NA Swinford, SP Prall, S Gopalan, CM Williams, J Sheehama, BA Scelza, BM Henn. Increased homozygosity due to endogamy results in fitness consequences in a human population. Proceedings of the National Academy of Sciences. 120(43):e2309552120. DOI: 10.1073/pnas.2309552120

2022

Z Lu*, S Gopalan*, D Yuan, DV Conti, B Pasaniuc, A Gusev, N Mancuso. (2022) Multi-ancestry fine-mapping improves precision to identify causal genes in transcriptome-wide association studies. The American Journal of Human Genetics. 109(8):1388-1404. DOI: 10.1016/j.ajhg.2022.07.002

S Gopalan, SP Smith, K Korunes, I Hamid, S Ramachandran, A Goldberg. (2022) Human genetic admixture through the lens of population genomics. Philosophical Transactions of the Royal Society B. 377(1852):202004103. DOI: 10.1098/rstb.2020.0410

S Gopalan*, REW Berl*, JW Myrick, ZH Garfield, AW Reynolds, BK Bafens, G Belbin, M Mastoras, C Williams, M Daya, AN Negash, MW Feldman, BS Hewlett, BM Henn. (2022) Hunter-gatherer genomes reveal diverse demographic trajectories during the rise of farming in Eastern Africa. Current Biology. 32(8):1852-1860.e5. DOI: 10.1016/j.cub.2022.02.050

JL Montalvo-Ortiz, J Gelernter, Z Cheng, MJ Girgenti, K Xu, X Zhang, S Gopalan, H Zhou, RS Duman, SM Southwick, JH Krystal, Traumatic Stress Brain Research Study Group, RH Pietrzak. (2022) Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans. Translational Psychiatry. 12(1):65. DOI: 10.1038/s41398-022-01822-3

2021

GA Pathak, K Singh, TW Miller-Fleming, FR Wendt, N Ehsan, K Hou, R Johnson, Z Lu, S Gopalan, L Yengo, P Mohammadi, B Pasaniuc, R Polimanti, LK Davis, N Mancuso. (2021) Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization. Nature Communications. 12:4569. DOI: 10.1038/s41467-021-24824-z

S Gopalan, EG Atkinson, LT Buck, TD Weaver, BM Henn. (2021) Inferring archaic introgression from hominin genetic data. Evolutionary Anthropology. 30(3):199-220. DOI: 10.1002/evan.21895

2020

BA Scelza, SP Prall, N Swinford, S Gopalan, EG Atkinson, R McElreath, J Sheehama, BM Henn. (2020) High rate of extrapair paternity in a human population demonstrates diversity in human reproductive strategies. Science Advances. 6:eaay6195. DOI: 10.1126/sciadv.aay6195

2017

L Botigue, S Song, A Scheu, S Gopalan, A Pendleton, M Oetjens, A Taravella, T Seregly, A Zeeb-Lanz, RM Arbogast, D Bobo, K Daly, M Unterländer, J Burger, J Kidd, KR Veeramah. (2017) Ancient European dog genomes reveal continuity since the early Neolithic. Nature Communications. 8:16082. DOI: 10.1038/ncomms16082

S Gopalan, O Carja, M Fagny, E Patin, JW Myrick, LM McEwen, SM Mah, MS Kobor, A Froment, MW Feldman, L Quintana-Murci, BM Henn. (2017) Trends in DNA methylation with age replicate across diverse human populations. Genetics. 206(3):1659-1674. DOI: 10.1534/genetics.116.195594

2015

Z Hofmanová, S Kreutzer, G Hellenthal, C Sell, Y Diekmann, D Díez del Molino, L van Dorp, S López, A Kousathanas, V Link, K Kirsanow, LM Cassidy, R Martiniano, M Strobel, A Scheu, K Kotsakis, P Halstead, S Triantaphyllou, N Kyparissi-Apostolika, D-C Urem-Kotsou, C Ziota, F Adaktylou, S Gopalan, DM Bobo, L Winkelbach, J Blöcher, M Unterländer, C Leuenberger, Ç Çilingiroğlu, B Horejs, F Gerritsen, S Shennan, DG Bradley, M Currat, KR Veeramah, D Wegmann, MG Thomas, C Papageorgopoulou, J Burger. (2015) Early farmers from across Europe directly descended from Neolithic Aegeans. Proceedings of the National Academy of Sciences. 113(25):6886-6891. DOI: 10.1073/pnas.1523951113

MJ Favé, RA Johnson, S Cover, S Handschuh, BD Metscher, GB Müller, S Gopalan, E Abouheif. (2015) Past climate change on sky islands drives novelty in a core developmental gene network and its phenotype. BMC Evolutionary Biology. 4(15):183. DOI: 10.1186/s12862-015-0448-4


Manuscripts in preparation

S Gopalan, J Gaige, BM Henn. DNA methylation-based forensic age estimation in human bone. Pre-print available on bioRxiv. DOI: 10.1101/801647